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Fully sequenced samples of complimentary DNA synthesized from single-stranded, mammalian RNA. Various gene inserts sourced from humans, mice, monkeys, and other species are available. Ideal for use in gene cloning, as gene probes, and in cDNA library creation.
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This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate The binding sites for each ligand are located on different segments of the protein This receptor has various functions including in the intracellular trafficking of lysosomal enzymes the activation of transforming growth factor beta and the degradation of insulin-like growth factor 2 Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele however imprinting of the human gene may be polymorphic as only a minority of individuals showed biased expression from the maternal allele (PMID 8267611)
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More